Disruptive Events in the Life of Prostate Cancer

作者:Brenner J Chad; Chinnaiyan Arul M*
来源:Cancer Cell, 2011, 19(3): 301-303.
DOI:10.1016/j.ccr.2011.02.020

摘要

Two recent reports in Nature provide evidence for increasingly complex "disruptive" molecular alterations that occur during prostate cancer progression. They shed light on the intricacy of genetic changes that modulate PTEN's control over the phosphoinositide 3-kinase pathway and prostate cancer progression, and identify new potential biomarkers and therapeutic targets.

  • 出版日期2011-3-15