Dangerous Liaisons: Mitochondrial DNA Meets the NLRP3 Inflammasome

作者：Martinon Fabio^*

来源：Immunity, 2012, 36(3): 313-315.

DOI：10.1016/j.immuni.2012.03.005

Danger signals released by damaged organelles can promote inflammation. In this issue of Immunity, Shimada et al. (2012) report that oxidized DNA, released by mitochondria, directly binds and activates the NLRP3 inflammasome.

• 出版日期2012-3-23