Convenient synthesis of 2-formyl-1,4,5,8-tetramethoxynaphthalene

作者：Xu, De Feng; Guan, Peng Jian; Li, Shao Shun^*

来源：Journal of Chemical Research, 2006, (12): 779-780.

• phase transfer catalytic
• 2-formyl-1,4,5,8-tetramethoxy naphthalene
• formylation

A convenient and concise synthesis of 1,4,5,8-tetramethoxynaphthalene can be achieved by methylation of 2,3-dihydronaphthazarin with dimethylsulfate in the presence of phase transfer catalytic in 90.3% yield, then formylation of 1,4,5,8-tetramethoxynaphthalene can afford 2-formyl-1,4,5,8-tetramethoxynaphthalene in 96.2% yield.

• 出版日期2006-12
• 单位上海交通大学