Itching in Patients with Chronic Hand Eczema: Data from the CARPE Registry

作者：Ruppert Linda; Apfelbacher Christian; Molin Sonja; Bauer Andrea; Mahler Vera; Schmitt Jochen; Elsner Peter; Diepgen Thomas L; Weisshaar Elke^*

来源：Dermatology, 2014, 229(2): 146-153.

DOI：10.1159/000362901

• Atopy
• Chronic hand eczema
• Dermatology Life Quality Index
• Eczema
• Itch
• Pruritus
• Quality of life
• CARPE registry

Background: Itching is a leading symptom of chronic hand eczema (CHE) having a great impact on patients. The determinants of itching in CHE are unclear. Objective: We performed a cross-sectional analysis investigating factors associated with the presence and severity of itch in CHE patients from the CARPE registry. Methods: We present baseline data on itch in relationship with sociodemographic factors, severity of CHE, atopy, contact allergy, treatment and patient-reported outcomes including health-related quality of life (HRQoL). Results: Of 1,051 patients with CHE, 78.1% reported itching. Significant positive associations with itching were observed for younger age groups (17-25 and 26-45 years), for moderate, severe and very severe CHE and for small/moderate impairment in HRQoL. Atopic skin diathesis, hardly being able to realize treatment recommendations and very or extremely large impairments in HRQoL were associated with itch severity. Conclusion: Taking the identified variables into account may help identify vulnerable groups most affected by (severe) itch.

• 出版日期2014