Dual Activation in N-Heterocyclic Carbene-organocatalysis

作者:Hirano Keiichi*; Piel Isabel; Glorius Frank
来源:Chemistry Letters, 2011, 40(8): 786-791.
DOI:10.1246/cl.2011.786

摘要

N-Heterocyclic carbene (NHC)-catalyzed transformations have found increasing interest in the last years. Recently, dual catalytic approaches using NHCs in combination with a second catalyst such as another organocatalyst or a metal-based catalyst or by the NHC itself have emerged. The careful choice of the proper combination of catalysts allows two compatible yet independent catalytic systems in one-pot to undergo tandem processes. Moreover, simultaneous action of two activators in a bond-forming event enables new reactivity, which often cannot be achieved by monocatalytic approaches.

  • 出版日期2011-8-5