科研之友
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摘要
Transferring mouse ESCs to a media supplemented with Mek and Gsk3 beta inhibitors (2i) provokes marked transcriptional and epigenetic changes, embodying a shift toward ground-state pluripotency. In this issue of Cell Stem Cell, Kolodziejczyk et al. (2015) examine population structures of ESCs while Galonska et al. (2015) unravel the mechanisms underlying regulatory network rewiring during 2i-mediated reprogramming.
- 出版日期2015-10-1
