Differential expression of microRNA-206 in skeletal muscle of female Piedmontese and Friesian cattle

作者：Miretti Silvia; Martignani Eugenio; Taulli Riccardo; Bersani Francesca; Accornero Paolo; Baratta Mario^*

来源：Veterinary Journal, 2011, 190(3): 412-413.

DOI：10.1016/j.tvjl.2010.12.012

• Muscular hypertrophy
• Piedmontese cattle
• MicroRNA

The double-muscle phenotype is an inherited condition in Piedmontese cattle traced to a point mutation in the myostatin gene. To investigate the potential role of muscle-specific miRNAs in determining muscle development in cattle, this study examined the patterns of expression of microRNAs (miRNA-1) and miRNA-206 in Piedmontese and Friesian cattle according to phenotype and sex. There were no significant differences in miRNA-1 expression between different muscle phenotypes, sexes or breeds, whereas there was significantly higher expression of miRNA-206 in female Piedmontese compared with female Friesian cattle.

• 出版日期2011-12