An electrochemical sensor for determination of tryptophan in the presence of DA based on poly(L-methionine)/graphene modified electrode

作者：Wang, Yingzi; Ouyang, Xiaoqian; Ding, Yaping^*; Liu, Bingdi; Xu, Duo; Liao, Lanfeng

来源：RSC Advances, 2016, 6(13): 10662-10669.

DOI：10.1039/c5ra24116b

• CARBON-PASTE ELECTRODE
• RAMAN-SPECTROSCOPY
• ASCORBIC-ACID
• URIC-ACID
• GRAPHENE OXIDE
• COMPOSITE FILM
• ACETAMINOPHEN
• NANOPARTICLES
• NANOTUBES
• NANOCOMPOSITE

A glassy carbon electrode modified with poly(L-methionine) and graphene composite film (PLME/GR/GCE) was fabricated by electropolymerization for determination of L-tryptophan (L-Trp) in the presence of dopamine (DA). The morphology and structure of the composite film were investigated by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy and electrochemical impedance spectroscopy (EIS). Differential pulse voltammetry (DPV) was utilized to investigate the electrocatalytical oxidation of L-Trp from the potentially interfering species on the PLME/ GR/GCE. Under optimum conditions, the proposed method exhibited a wide linear dynamic range 0.2-150 mu M, with a detection limit (S/N = 3), and good reproducibility and high selectivity. Moreover, the proposed modified electrode has been successfully applied to determine L-Trp in milk and human serum samples.

• 出版日期2016
• 单位上海大学