Dual-Pathway Sequences for MR Thermometry: When and Where to Use Them

作者：Ciris, Pelin Aksit; Cheng, Cheng-Chieh; Mei, Chang-Sheng^*; Panych, Lawrence P.; Madore, Bruno

来源：Magnetic Resonance in Medicine, 2017, 77(3): 1193-1200.

DOI：10.1002/mrm.26177

• MR thermometry
• multipathway sequences
• temperature-to-noise ratio
• PSIF
• DESS
• proton resonance frequency shift

Purpose: Dual-pathway sequences have been proposed to help improve the temperature-to-noise ratio (TNR) in MR thermometry. The present work establishes how much of an improvement these so-called "PSIF-FISP" sequences may bring in various organs and tissues. @@@ Methods: Simulations and TNR calculations were validated against analytical equations, phantom, abdomen, and brain scans. Relative TNRs for PSIF-FISP, as compared to a dualFISP reference standard, were calculated for flip angle (FA) = 1 to 85 degrees and repetition time (TR) = 6 to 60 ms, for gray matter, white matter, cervix, endometrium, myometrium, prostate, kidney medulla and cortex, bone marrow, pancreas, spleen, muscle, and liver tissues. @@@ Results: PSIF-FISP was TNR superior in the kidney, pelvis, spleen, or gray matter at most tested TR and FA settings, and benefits increased at shorter TRs. PSIF-FISP was TNR superior in other tissues, e. g., liver, muscle, pancreas, for only short TR settings (20 ms or less). The TNR benefits of PSIF-FISP increased slightly with FA, and strongly with decreasing TR. Up to two-to three-fold reductions in TR with 20% TNR gains were achievable. In any given tissue, TNR performance is expected to further improve with heating, due to changes in relaxation rates. @@@ Conclusion: Dual-pathway PSIF-FISP can improve TNR and acquisition speed over standard gradient-recalled echo sequences, but optimal acquisition parameters are tissue dependent.

• 出版日期2017-3
• 单位苏州大学