Drug reaction with eosinophilia and systemic symptoms during primary Epstein-Barr virus infection

作者：Nanishi Etsuro; Hoshina Takayuki^*; Ohga Shouichi; Nishio Hisanori; Hara Toshiro

来源：Journal of Microbiology, Immunology, and Infection, 2015, 48(1): 109-112.

DOI：10.1016/j.jmii.2014.06.012

• acetaminophen
• cefditoren-pivoxil
• drug reaction with eosinophilia and systemic symptoms
• Epstein-Barr virus
• lymphocyte transformation test

We report a drug reaction with eosinophilia and systemic symptoms case of primary Epstein-Barr virus (EBV) infection, in which the diagnosis was first confirmed by lymphocyte transformation tests (LTT). LTTs were positive for cefditoren-pivoxil and acetaminophen. LTT, EBV load, and anti-EBV antibodies could allow early diagnosis of drug reaction with eosinophilia and systemic symptoms, which masquerades with the clinical features of infectious mononucleosis.

• 出版日期2015-2