An Efficient Access to Aspermytin A and Oblongolide C through an Intramolecular Nitrile Oxide-Alkene [3+2] Cycloaddition

作者：Inoue Atsushi; Kanematsu Makoto; Mori Seiji; Yoshida Masahiro; Shishido Kozo^*

来源：Synlett, 2013, 24(1): 61-64.

DOI：10.1055/s-0032-1317693

• total synthesis
• enantioselectivity
• cycloaddition
• aspermytin A
• nitrile oxide

The second generation synthesis of (+)-aspermytin A and the first total synthesis of (-)-oblongolide C have been accomplished employing an intramolecular nitrile oxide-alkene [3+2] cycloaddition as the key step.

• 出版日期2013-1