Appendiceal and rectal carcinomas with Krukenberg tumour mimicking primary ovarian cancer

作者：Saba Ayesha; Khan Rozilla Sadia^*; Ismail Humera

来源：Journal of Pakistan Medical Association, 2018, 68(2): 284-286.

• Krukenberg Tumour
• Ovarian Tumours
• Metastatic Tumours

Krukenberg tumour is an uncommon metastatic tumour of ovary. It accounts for 1-2% of ovarian malignancies. Pylorus of stomach is the most common site of primary tumour. We are presenting two case reports of patients who had Krukenberg ovarian masses. Case I; an appendiceal adenocarcinoma (AACa) which manifested clinically as primary ovarian cancer. Staging laparotomy revealed large right side ovarian tumour of clinical FIGO Stage III. Histological examination revealed a poorly differentiated adenocarcinoma which involved right ovary and appendix. Immunophenotypic analysis revealed positive expression of Cytokeratin (CK) 20 and CDX2 which was compatible with appendiceal primary and ovarian metastases. Case 2; 60 years female with right adnexal and rectal masses. Histology revealed a moderately differentiated adenocarcinoma of rectum, CK7 was negative. CK20 and CDX2 were positive. Large bowel was the primary tumour site. Distinction between ovarian, rectal and appendiceal primary malignancies is critical as the treatment modalities vary.

• 出版日期2018-2