科研之友
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摘要
2-(Chloroseleno)benzoyl chloride serves as a versatile building block for the synthesis of novel ebselen (2-phenyl-1,2-benzisoselenazol-3(2H)-one) analogues and benzo[b]selenophen-3(2H)-one derivatives. The antioxidant activity and cytotoxic evaluation of the newly synthesized compounds were implemented. Among all the synthesized compounds, 1-(3-hydroxybenzo[b]selenophen-2-yl)ethanone oxime (9) was the most potent antioxidant and the most cytotoxic compound as well.
- 出版日期2018-7
