Detection of hepatitis B virus in the cerumen of patients with chronic hepatitis B infection

作者：Eftekharian A^*; Moghaddasi H; Gachkar L; Amlashi S S A

来源：Journal of Laryngology and Otology, 2013, 127(11): 1065-1066.

DOI：10.1017/S0022215113002314

• Hepatitis B Virus
• Cerumen
• Chronic Hepatitis

Objective: To investigate hepatitis B virus DNA in the cerumen of hepatitis B virus infected patients.
Methods: This study comprised 30 confirmed cases of chronic hepatitis B. Patients' serum samples were examined for hepatitis B surface antigen and antibodies using enzyme immunoassay systems. The presence of hepatitis B virus DNA in cerumen was investigated using a polymerase chain reaction test.
Results: All of the samples were positive for hepatitis B surface antigen and negative for hepatitis B surface antibodies. Hepatitis virus DNA was detected in two cerumen samples (6.6 per cent of patients).
Conclusion: Cerumen can be a potential source of transmission of hepatitis B virus.

• 出版日期2013-11