A facile approach to highly functional trisubstituted furans via intramolecular Wittig reactions

作者:Chen Ko Wei; Syu Siang en; Jang Yeong Jiunn; Lin Wenwei*
来源:Organic and Biomolecular Chemistry, 2011, 9(7): 2098-2106.
DOI:10.1039/c0ob00912a

摘要

An efficient and mild synthesis of trisubstituted furans, starting from alpha,beta-unsaturated ketones, tributylphosphine, and acyl chlorides, is described. The strategy employs the intramolecular Wittig protocol as a key step to install the crucial furan ring, leading to a wide variety of highly functional furans in one step.

  • 出版日期2011