Abdominal Adhesions: Current and Novel Therapies

作者：Ward Brian C; Panitch Alyssa^*

来源：Journal of Surgical Research, 2011, 165(1): 91-111.

DOI：10.1016/j.jss.2009.09.015

• abdominal
• adhesion
• therapy
• review
• inflammation
• fibrosis
• cytokine

An adhesion occurs when two tissues that normally freely move past each other attach via a fibrous bridge. Abdominal adhesions place a tremendous clinical and financial burden on public health. Adhesions develop after nearly every abdominal surgery, commonly causing female infertility, chronic pelvic pain, and, most frequently, small bowel obstruction. A National Hospital Discharge Survey of hospitalizations between 1998 and 2002 reported that 18.1% of hospitalizations were related to abdominal adhesions annually accounting for 948,000 days of inpatient care at an estimated cost of $1.18 billion.
This review discusses the current or proposed therapies for abdominal adhesions. While many therapies for abdominal adhesions have been attempted, the need for a definitive therapy to prevent or even reduce abdominal adhesions still exists.

• 出版日期2011-1