A Composite Renal Tumor: Metanephric Adenofibroma, Wilms Tumor, and Renal Cell Carcinoma: A Missing Link?

作者：Galluzzo Maria Laura; Garcia de Davila Maria T; Vujanic Gordan M^*

来源：Pediatric and Developmental Pathology, 2012, 15(1): 65-70.

DOI：10.2350/11-03-1007-CR.1

• composite renal tumor
• metanephric adenofibroma
• renal cell carcinoma
• Wilms tumor

A coexistence of different renal tumors has rarely been reported. The most commonly described association is of Wilms tumor and renal cell carcinoma. Metanephric adenofibroma has also been associated with Wilms tumor or papillary renal cell carcinoma. Another reported association is metanephric adenoma and papillary renal cell carcinoma with sarcomatoid dedifferentiation. Herein we describe a complex renal tumor containing areas of metanephric adenofibroma, Wilms tumor, and undifferentiated renal cell carcinoma in a previously healthy 18-year-old boy. The tumor showed histologic and immunohistochemical features of these 3 different tumors, offering additional support to the view that these 3 tumors are related.

• 出版日期2012-2