A NOVEL FLT4 GENE MUTATION AND MR LYMPHANGIOGRAPHY IN A CHINESE FAMILY WITH MILROY DISEASE

作者：Liu, N F^*; Yu, Z; Luo, Y; Sun, D; Yan, Z

来源：Lymphology, 2015, 48(2): 93-96.

• Milroy disease
• FLT4
• VEGFR-3
• primary lymphedema
• novel gene mutation
• MR lymphangiogram
• phenotype

Milroy disease is a congenital onset lymphedema linked to FLT4 gene mutations in the tyrosine kinase domain. So far, a total of 59 different FLT4 variants have been identified. Here, we report a novel FLT4 gene mutation in a Chinese family with Milroy disease and present their clinical symptoms and MR lymphangiographic findings.

• 出版日期2015-6
• 单位上海交通大学