An Aromatic Amination Approach towards Ancistrocladinium A/B

作者：Buckley Benjamin R; Christie Steven D R^*; Elsegood Mark R J; Gillings Claire M; Page Philip C Bulman; Pardoe William J M

来源：Synlett, 2010, (6): 939-943.

DOI：10.1055/s-0029-1219561

• amination
• natural products
• palladium
• Buchwald-Hartwig
• tetrahydroquinoline
• tetrahydroisoquinoline

We report a high yielding approach to N-aryl tetrahydroisoquinolines and tetrahydroquinolines in one step from readily available starting materials. We have used this methodology to prepare the full carbon skeleton of the ring system of ancistrocladinium A in one step.

• 出版日期2010-4