A Viral (Arc)hive for Metazoan Memory

作者:Parrish Nicholas F; Tomonaga Keizo*
来源:Cell, 2018, 172(1-2): 8-10.
DOI:10.1016/j.cell.2017.12.029

摘要

Arc, a master regulator of synaptic plasticity, contains sequence elements that are evolutionarily related to retrotransposon Gag genes. Two related papers in this issue of Cell show that Arc retains retroviral-like capsid-forming ability and can transmit mRNA between cells in the nervous system, a process that may be important for synaptic function.

  • 出版日期2018-1-11