Direct Synthesis of Arylketones by Nickel-Catalyzed Addition of Arylboronic Acids to Nitriles

作者：Wong Ying Chieh; Parthasarathy Kanniyappan; Cheng Chien Hong^*

来源：Organic Letters, 2010, 12(8): 1736-1739.

DOI：10.1021/ol1003252

A convenient and efficient method for the synthesis of various arylketones by nickel-catalyzed addition of arylboronic acids to nitriles is described. A catalytic cycle involving Ni(II) species as the catalytic intermediates is proposed to account for the present catalytic reaction.

• 出版日期2010-4-16
• 单位清华大学