Mechanisms of cramp contractions: peripheral or central generation?

作者:Minetto Marco Alessandro*; Holobar Ales; Botter Alberto; Ravenni Roberta; Farina Dario
来源:The Journal of Physiology, 2011, 589(23): 5759-5773.
DOI:10.1113/jphysiol.2011.212332

摘要

Non-technical summary There is still a debate on the origin of muscle cramps, which may be from the peripheral or the central nervous system. In this study we show that cramps electrically induced in the abductor hallucis of healthy men do occur with and without a proximal nerve block. However, cramps elicited during the nerve block required greater stimulation frequency, lasted for a substantially shorter interval, and presented different motor unit behaviour with respect to cramps induced without the block. These findings suggest the relevance of spinal involvement in both the origin and sustenance of muscle cramps.

  • 出版日期2011-12