New hybrid materials based on layered double hydroxides and antioxidant compounds. Preparation, characterization and release kinetic studies

作者：Silion Mihaela; Hritcu Doina; Lisa Gabriela; Popa Marcel Ionel^*

来源：Journal of Porous Materials, 2012, 19(3): 267-276.

DOI：10.1007/s10934-011-9473-x

• Layered double hydroxide
• Vanillic acid
• Gallic acid
• Antioxidant compounds
• Controlled release

New hybrid materials were obtained by intercalation of the antioxidant compounds vanillic acid and gallic acid in layered double hydroxides (LDHs) resulting formulations with controlled release and antioxidant activity. The hybrid materials were prepared by using two methods: coprecipitation and ion exchange. X-ray powder diffraction, infrared spectroscopy and thermogravimetric analysis confirmed that the antioxidant molecules were intercalated into interlayer spaces of LDHs. The release of the antioxidant compounds was investigated in simulated gastrointestinal solution at 37 A degrees C and monitored using a spectrophotometric method. The results prove that these hybrid biocomposites can be classified as controlled release formulations for the antioxidant compounds under study.

• 出版日期2012-6