Adenoidectomy can improve obstructive sleep apnoea in young children: systematic review and meta-analysis

作者：Reckley L K^*; Song S A; Chang E T; Cable B B; Certal V; Camacho M

来源：Journal of Laryngology and Otology, 2016, 130(11): 990-994.

DOI：10.1017/S0022215116008938

• Adenoidectomy
• Sleep Apnea Syndromes
• Review
• Systematic
• Meta-Analysis

Objective: To systematically search for studies reporting outcomes for adenoidectomy alone as a treatment for paediatric obstructive sleep apnoea and use the data to perform a meta-analysis.
Methods: Nine databases, including PubMed and Medline, were systematically searched through to 1 April 2016. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement was followed.
Results: A total of 1032 articles were screened and 126 full texts were reviewed. Three paediatric studies (47 patients) reported outcomes. Overall, apnoea-hypopnoea index values decreased from 18.1 +/- 16.8 to 3.1 +/- 5.5 events per hour (28 patients). Random-effects modelling demonstrated a mean difference of-14.43 events per hour (I-2 = 23 per cent (low inconsistency)). The apnoea-hypopnoea index standardised mean difference was -1.14 (large magnitude of effect). The largest reduction in apnoea-hypopnoea index was observed in children aged less than 12 months (reduction of 56.6-94.9 per cent). Lowest oxygen saturation values improved from 80.0 +/- 9.5 to 85.5 +/- 6.0 per cent (13 children).
Conclusion: Adenoidectomy alone has improved obstructive sleep apnoea in children, especially in those aged less than 12 months; however, given the low number of studies, isolated adenoidectomy remains an area for additional research.

• 出版日期2016-11