An efficient synthesis of 6-arylbenzo[4,5]imidazo[2,1-a]isoquinolines via sequential alpha-arylation of carbonyl and deacylation catalyzed by CuI

作者：Miao Wei Qing; Liu Jian Quan; Wang Xiang Shan

来源：Organic and Biomolecular Chemistry, 2017, 15(25): 5325-5331.

DOI：10.1039/c7ob01022b

Dibenzoyl methane was found to undergo α-arylation of carbonyl and deacylation reaction with 2-(2-bromophenyl)-1H-benzo[d]imidazoles catalyzed by CuI in the presence of Cs2CO3, and provided an efficient synthesis of 6-arylbenzo[4,5]imidazo[2,1-a]isoquinolines.

• 出版日期2017-7-7