Molecular Landscape of Non-Muscle Invasive Bladder Cancer

作者：Meeks Joshua J; Lerner Seth P^*

来源：Cancer Cell, 2017, 32(5): 550-551.

DOI：10.1016/j.ccell.2017.08.015

In this issue of Cancer Cell, Hurst et al. report an integrated analysis of non-invasive (stage Ta) bladder cancer. Two genomic subtypes are distinguished by chromosome 9q loss, resulting in increased AKT/PI3K/mTOR signaling. Tumors from female patients have a higher frequency of KDM6A mutations.

• 出版日期2017-11-13
• 单位西北大学