Mannose-binding lectin (MBL2) polymorphisms and inflammation in hypertensive patients

作者：Schreiber R; Campos Coelho A V; Brandao L; Guimaraes R L; Kamada A J; Ferreira Sae M C; Matos Souza J R; Cipolli J A; de Lima Filho J L; Crovella S^*; Nadruz W Jr

来源：International Journal of Immunogenetics, 2011, 38(6): 525-527.

DOI：10.1111/j.1744-313X.2011.01036.x

We investigated the possible role of Mannose binding lectin 2 (MBL2) functional polymorphisms in the prevalence of hypertension and hypertensive end-organ damage in 300 hypertensive patients and 313 normotensive individuals from Southern Brazil. Hypertensive subjects with MBL2 AO/OO genotypes presented lower C-reactive protein levels than AA individuals and consequently lower inflammatory status.

• 出版日期2011-12