Age at symptom onset is not associated with reduced action cancelation in adults with obsessive-compulsive disorder

作者：Lei, Hui; Zhong, Mingtian; Fan, Jie; Zhang, Xiaocui; Cai, Lin; Zhu, Xiongzhao^*

来源：Psychiatry Research, 2017, 252: 180-184.

DOI：10.1016/j.psychres.2017.02.063

• Response inhibition
• Action cancelation
• Obsessive-compulsive disorder
• Early-onset
• Late-onset

The aim of the current study was to examine the association between age at symptom onset and action cancelation in adults with obsessive-compulsive disorder (OCD). Performance on the stop-signal task was compared among adult patients with early-onset OCD (n=63, onset age <= 19), late-onset OCD (n=33, onset age >= 20), and healthy controls (n=51). Stop-signal reaction time (SSRT) was significantly longer in both OCD groups compared to the control group. However, no significant differences were found between the two OCD groups. In addition, age at symptom onset was not associated with response inhibition performance in adults with OCD. The study findings support the existence of reduced performance on action cancelation in patients with OCD compared to healthy controls with no difference between early- and late-onset OCD subtypes.

• 出版日期2017-6
• 单位中南大学; 湖南农业大学; 西南民族大学