Determination of elements in different parts of goat brain using k (0) instrumental neutron activation analysis

作者：Wasim Mohammad^*; Arif Mohammad; Iqbal Mohammad S

来源：Journal of Radioanalytical and Nuclear Chemistry, 2014, 300(1): 249-254.

DOI：10.1007/s10967-014-2978-4

• Goat brain
• k(0)-INAA
• Elemental analysis
• Principal component analysis

Researcher's interest is increasing worldwide to study the role of trace elements in brain tissues. This paper discusses the application of k (0)-instrumental neutron activation analysis to study the distribution of trace elements in seven different anatomical regions of goat brain. These regions include cerebellum, cerebrum, medulla oblongata, meninges, midbrain, pons and thalamus. The analysis protocol followed 1 h irradiation at 10 MW material testing type nuclear research reactor with nominal thermal neutron flux of 2 x 10(13) cm(-2) s(-1). A total of 14 elements, namely Br, Co, Cr, Eu, Fe, Hg, K, Na, Rb, Sb, Sc, Se, Tb and Zn were determined in all parts. Reliability of the method was assessed by analyzing biological reference material IAEA-336 (lichen). On comparing the analytical results with the healthy human brain data, it showed that eight elements (Eu, K, Na, Rb, Sb, Sc, Se, Tb) were found with relatively higher elemental concentrations in human brain. Principal component analysis revealed distribution of seven parts in different three groups having similar elemental concentrations of elements.

• 出版日期2014-4