Design and Characterization of Porous Titanium Scaffold for Bone Tissue Engineering

作者：Deng Zhenbo; Zhou Changchun; Fan Yujiang; Peng Jingping; Zhu Xiangdong; Pei Xuan; Yin Guofu^*; Zhang Xingdong

来源：Rare Metal Materials and Engineering, 2016, 45(9): 2287-2292.

• porous titanium
• bone tissue engineering
• parametric modeling
• laser selective melting 3D printing
• porous structures

In order to fabricate bone tissue engineering scaffold accurately, a novel method that combined parametric modeling and 3D printing was proposed. In this method, the scaffold structures were designed using cloud data of the molded surface. Firstly, the cloud data containing the surface information of cube structure, diamond structure and gyroid structure were obtained. Then the scaffold structures with different parameters were expressed by mathematical functions. After that, finite element analysis was done to the scaffolds. The mechanical properties of porous scaffolds were calculated based on the finite element analysis. Bone tissue engineering scaffolds with different porous structures were manufactured by 3D printing. Finally, the printed titanium scaffolds were characterized to detect the porosity and mechanical properties. The results show that the parameterized model and rapid prototyping manufacturing can design and fabricate titanium alloy scaffolds with specific pore structure characteristics effectively. And the scaffold's mechanical properties can be also designed. It optimizes the design of porous titanium alloy scaffolds with biological functions from the perspective of bionics.

• 出版日期2016-9
• 单位四川大学