Designing BODIPY-based probes for fluorescence imaging of beta-amyloid plaques

作者：Sozmen Fazli; Kolemen Safacan; Kumada Henri Obadja; Ono Masahiro; Saji Hideo; Akkaya Engin U^*

来源：RSC Advances, 2014, 4(92): 51032-51037.

DOI：10.1039/c4ra07754g

Styryl-congutated BODIPY dyes which are structurally similar to known A beta peptide binding dyes, were designed and synthesized. The binding is accompanied by a large increase in the emission intensity in all cases, suggesting a high potential for use in the fluorescence imaging of A beta plaques.

• 出版日期2014