Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool

作者：Hoenen Thomas^*; Groseth Allison; Rosenke Kyle; Fischer Robert J; Hoenen Andreas; Judson Seth D; Martellaro Cynthia; Falzarano Darryl; Marzi Andrea; Squires R Burke; Wollenberg Kurt R; de Wit Emmie; Prescott Joseph; Safronetz David; van Doremalen Neeltje; Bushmaker Trenton; Feldmann Friederike; McNally Kristin; Bolay Fatorma K; Fields Barry; Sealy Tara; Rayfield Mark; Nichol Stuart T; Zoon Kathryn C; Massaquoi Moses; Munster Vincent J; Feldmann Heinz

来源：Emerging Infectious Diseases, 2016, 22(2): 331-334.

DOI：10.3201/eid2202.151796

Rapid sequencing of RNA/DNA from pathogen samples obtained during disease outbreaks provides critical scientific and public health information. However, challenges exist for exporting samples to laboratories or establishing conventional sequencers in remote outbreak regions. We successfully used a novel, pocket-sized nanopore sequencer at a field diagnostic laboratory in Liberia during the current Ebola virus outbreak.

• 出版日期2016-2