A TGF-beta pathway associated with cancer cachexia

作者:Guttridge Denis C*
来源:Nature Medicine, 2015, 21(11): 1248-1249.
DOI:10.1038/nm.3988

摘要

Cancer cachexia leads to involuntary weight loss resulting from the atrophy of skeletal muscle and adipose tissues. Now, in metastatic mouse models of cancer, investigators reveal a cross talk pathway between bone and muscle that provides a new understanding of wasting in advanced cancers.

  • 出版日期2015-11