Gold meets enamine catalysis in the enantioselective alpha-allylic alkylation of aldehydes with alcohols

作者:Chiarucci Michel; di Lillo Marzia; Romaniello Alessandro; Cozzi Pier Giorgio; Cera Gianpiero; Bandini Marco*
来源:Chemical Science, 2012, 3(9): 2859-2863.
DOI:10.1039/c2sc20478a

摘要

Synergetic gold(I)- and organo-catalysis proved to be efficient towards the intramolecular stereoselective alpha-allylic alkylation of aldehydes with simple primary and secondary alcohols. High diastereo- and enantioselectivity were recorded.

  • 出版日期2012