Neurogenesis and Maturation in Neonatal Brain Injury

作者：Salmaso Natalina; Tomasi Simone; Vaccarino Flora M^*

来源：Clinics in Perinatology, 2014, 41(1): 229-+.

DOI：10.1016/j.clp.2013.10.007

• Preterm birth
• Neurogenesis
• Neonatal brain injury
• Cognitive delay

The incidence of preterm birth is on the rise. The outcome of premature birth can vary widely, spanning completely normal development to severe neurologic deficits, with most children showing mild to moderate cognitive delay and increased incidence of neuropsychiatric conditions such as anxiety, attention deficit hyperactivity, and autism spectrum disorders. Several animal models have been employed to study the consequences of prematurity, one of the most promising being chronic perinatal hypoxia in mouse, which recapitulates the cognitive impairments, partial recovery over time and enhanced recovery with environmental enrichment.

• 出版日期2014-3