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摘要
A new apiose-containing kaempferol trioside, kaempferol-3-O-alpha-l-rhamnosyl-(1"'-> 6 '')-O-beta-d-galactopyranosyl-7-O-beta-d-apiofuranoside, along with 16 known compounds, were isolated from 50% acetone extract of Silphium perfoliatum L. Their structures were elucidated by acid hydrolysis and spectroscopic techniques including UV, IR, MS, H-1, C-13, and 2D-NMR. In addition, the pharmacological activity of compound 1 was tested with HepG2 and Balb/c mice (splenic lymphocytes and thymic lymphocytes) in vitro, and it exhibited inhibitory effect on the proliferation of HepG2 cells and showed the immunosuppressive activity.
- 出版日期2014-4-3
- 单位河南中医药大学
