Antisolvent Precipitation of Vitamin B6: A Thermodynamic Study

作者:Kikic I*; De Zordi N; Moneghini M; Solinas D
来源:Journal of Chemical and Engineering Data, 2011, 56(12): 4978-4983.
DOI:10.1021/jr200853g

摘要

A supercritical antisolvent precipitation process was applied to recrystallize vitamin B(6) from ethanol solution in CO(2). By means of the Peng-Robinson equation of state (PR EoS), we performed preliminary studies to identify better operative conditions in terms of the organic solvent, pressure, temperature, and ability to carry a precipitate of the solute. This simulation was also considered to estimate the vitamin B(6) particle size starting from supersaturation conditions.

  • 出版日期2011-12