A CMOS blood cancer detection sensor based on frequency deviation detection

作者:Nagulapalli Rajasekhar; Hayatleh Khaled*; Barker Steve; Raparthy Sumathi; Lidgey F John
来源:Analog Integrated Circuits and Signal Processing, 2017, 92(3): 437-442.
DOI:10.1007/s10470-017-1008-1

摘要

This paper proposes a technique to detect Leukaemia (blood cancer) based on the frequency modulation of a relaxation oscillator by changes in the dielectric constant of blood cells. A novel 16-bit frequency detector with a digital output has been proposed to detect the frequency difference between two oscillators based on healthy blood and Leukaemic blood. A circuit has been designed, to operate on a 1.2 V supply, post layout simulations shows 0.35 mA current consumption. The chip Area including pads similar to 0.6 mm x 0.45 mm.

  • 出版日期2017-9