Lysogenic Transfer of mef(A) and tet(O) Genes Carried by Phi m46.1 among Group A Streptococci

作者:Di Luca Maria Chiara; D'Ercole Stefania; Petrelli Dezemona; Prenna Manuela; Ripa Sandro; Vitali Luca A*
来源:Antimicrobial Agents and Chemotherapy, 2010, 54(10): 4464-4466.
DOI:10.1128/AAC.01318-09

摘要

We report the ex vivo lysogenic transfer of erythromycin and tetracycline resistance genes among group A streptococci (GAS). Of 42 susceptible strains, 69% acquired erythromycin/tetracycline resistance when infected with purified supernatants from strain m46 culture containing the phage Phi m46.1. A significant emm-type-dependent barrier to lysogenic transfer was not observed. The emm12 strains were the only strains susceptible to the lytic action of the bacteriophage preparation.

  • 出版日期2010-10