Diagnostic pitfalls with Cushing's syndrome

作者：Hunger Battefeld W^*; Gajda M; Hansch A; Mandecka A; Mueller U A; Wolf G

来源：Internist, 2010, 51(S1): 293-301.

DOI：10.1007/s00108-009-2493-9

• Cushing's syndrome
• Hypercortisolism
• Adrenal cortical carcinoma
• Corticosteroids

Adrenal cortical carcinoma is a rare diagnosis and may present with hormone secretion. A histological differentiation between an adrenal cortical adenoma and carcinoma can be very difficult. However, a fast diagnosis including staging and complete surgical resection is pivotal for the prognosis of an adrenal cortical carcinoma. Metastasing adrenal cortical carcinoma should be treated with a mitotane based chemotherapy, and inclusion in the "firm-act study" is highly recommended. The present case report demonstrates the diagnostic pitfalls in a female patients with Cushing's syndrome who suffered from metastasing adrenal cortical carcinoma.

• 出版日期2010-3