Bone Mineral Density Increases in HIV-Infected Children Treated With Long-term Combination Antiretroviral Therapy

Bunders Madeleine J<sup>*</sup>; Frinking Olivier; Scherpbier Henriette J; van Arnhem Lotus A; van Eck Smit Berthe L; Kuijpers Taco W; Zwinderman Aeilko H; Reiss Peter; Pajkrt Dasja

doi:10.1093/cid/cis917

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Bone Mineral Density Increases in HIV-Infected Children Treated With Long-term Combination Antiretroviral Therapy

作者：Bunders Madeleine J^*; Frinking Olivier; Scherpbier Henriette J; van Arnhem Lotus A; van Eck Smit Berthe L; Kuijpers Taco W; Zwinderman Aeilko H; Reiss Peter; Pajkrt Dasja

来源：Clinical Infectious Diseases, 2013, 56(4): 583-586.

DOI：10.1093/cid/cis917

摘要

The long-term treatment of human immunodeficiency virus (HIV)-infected children with combination antiretroviral therapy (cART) requires assessment of potential adverse effects, such as osteoporosis. Longitudinal data on bone mineral density (BMD) in HIV-infected children showed that cumulative treatment with cART had a positive impact on BMD over time.