摘要

In order to perform an Osteochondral Autologous Transplantation (OAT) or an Autologous Chondrocyte Implantation (ACI), the integrity of healthy intact articular cartilage at a second location needs to be violated. This creates the possibility for donor site morbidity. Only recently have any publications addressed this issue. The aim of this manuscript is to review the current knowledge on donor site morbidity after an OAT or an ACI.
Reports were identified by searching Medline and Pubmed up to March 2010. Donor site morbidity was described mostly considering a clinical outcome, both in a qualitative (parameters in history or physical examination) and/or quantitative way (knee status by means of a numerical score). An increasing rate problems is noted when using quantitative instead qualitative parameters, and when donor site is the focus of attention, affecting up to more than of the patients, in particular for an OAT procedure.
The decision to harvest an osteochondral or biopsy to perform a repair procedure should be taken with caution. This also underscores the for further research to identify safe donor sites or develop techniques that eliminate the need for a biopsy ccompletely.

  • 出版日期2010-10