HAEMATOLOGICAL CANCER Richter's transformation in CLL-a distinct lymphoma

作者:Jain Preetesh; Young Ken H*
来源:Nature Reviews Clinical Oncology, 2014, 11(1): 6-8.
DOI:10.1038/nrclinonc.2013.229

摘要

A landmark study has delineated and identified the genetic pathways that drive the natural course of chronic lymphocytic leukaemia (CLL) B cells into Richter's transformation. CLL-related Richter's transformation is a distinct lymphoma, and poses various questions about B-cell ontogeny and relevance of B cell receptor signalling inhibitors.

  • 出版日期2014-1