Design and Validation of a Method for Evaluation of Interocular Interaction

作者：Lai Xin Jie^*; Alexander Jack; Ho Arthur; Yang Zhikuan; He Mingguang; Suttle Catherine

来源：Optometry and Vision Science, 2012, 89(2): 183-196.

DOI：10.1097/OPX.0b013e31823ee04a

• interocular interaction
• dichoptic
• low-contrast acuity
• contrast sensitivity
• alignment sensitivity

Purpose. To design a simple viewing system allowing dichoptic masking, and to validate this system in adults and children with normal vision. %26lt;br%26gt;Methods. A Trial Frame Apparatus (TFA) was designed to evaluate interocular interaction. This device consists of a trial frame, a 1 mm pinhole in front of the tested eye and a full or partial occluder in front of the non-tested eye. The difference in visual function in one eye between the full-and partial-occlusion conditions was termed the Interaction Index. In experiment 1, low-contrast acuity was measured in six adults using five types of partial occluder. Interaction Index was compared between these five, and the occluder showing the highest Index was used in experiment 2. In experiment 2, low-contrast acuity, contrast sensitivity, and alignment sensitivity were measured in the non-dominant eye of 45 subjects (15 older adults, 15 young adults, and 15 children), using the TFA and an existing well-validated device (shutter goggles) with full and partial occlusion of the dominant eye. These measurements were repeated on 11 subjects of each group using TFA in the partial-occlusion condition only. Repeatability of visual function measurements using TFA was assessed using the Bland-Altman method and agreement between TFA and goggles in terms of visual functions and interactions was assessed using the Bland-Altman method and t-test. %26lt;br%26gt;Results. In all three subject groups, the TFA showed a high level of repeatability in all visual function measurements. Contrast sensitivity was significantly poorer when measured using TFA than using goggles (p %26lt; 0.05). However, Interaction Index of all three visual functions showed acceptable agreement between TFA and goggles (p %26gt; 0.05). %26lt;br%26gt;Conclusions. The TFA may provide an acceptable method for the study of some forms of dichoptic masking in populations where more complex devices (e. g., shutter goggles) cannot be used. (Optom Vis Sci 2012; 89: 183-196)

• 出版日期2012-2