A feature parameter of optical diffuse reflectance on normal and malignant human breast tissue

作者：Zhang Lianshun^*

来源：Journal of Modern Optics, 2009, 56(5): 632-637.

DOI：10.1080/09500340802713137

• biological tissue
• optical diffuse reflectance
• Monte Carlo simulation
• feature parameter

Light that is delivered to the tissue surface undergoes multiple elastic scattering and absorption; part of it returns to the surface as optical diffuse reflectance, carrying quantitative information on the structure and composition of the measured tissue. In this paper, we utilized a well tested and publicly available Monte Carlo simulation software to simulate optical diffuse reflectance on normal and malignant human breast tissue in the visible wavelength region 450-650 nm. Based on the Monte Carlo simulation results, we discovered a feature parameter of optical diffuse reflectance on the simulated tissue surface. Normal and malignant human breast tissue may be discriminated by the value of the feature parameter. The values of the feature parameter are shown for normal and malignant human breast tissue in the visible wavelength region 450-650 nm. Experiments with tissue phantoms showed that the feature parameter is correlated to the component of the phantom. So the feature parameter is useful for the non-invasive optical diagnosis of biological tissue.

• 出版日期2009
• 单位中国民航大学