A simple acylation of thiols with anhydrides

作者：Temperini Andrea^*; Annesi Diego; Testaferri Lorenzo; Tiecco Marcello

来源：Tetrahedron Letters, 2010, 51(41): 5368-5371.

DOI：10.1016/j.tetlet.2010.07.126

• Thiol esters
• Acylation
• Thiols

Different thiols were efficiently acylated at room temperature with different anhydrides in the presence of potassium carbonate. Chemoselective protection of thiol in the presence of hydroxy group was achieved using di-tert-butyl dicarbonate and isatoic anhydride.

• 出版日期2010-10-13