Feasibility of in vivo intravascular photoacoustic imaging using integrated ultrasound and photoacoustic imaging catheter

作者：Karpiouk Andrei B; Wang Bo; Amirian James; Smalling Richard W; Emelianov Stanislav Y^*

来源：Journal of Biomedical Optics, 2012, 17(9): 096008.

DOI：10.1117/1.JBO.17.9.096008

• in vivo
• intravascular
• photoacoustic imaging
• ultrasound imaging
• intravascular ultrasound/intravascular photoacoustic
• stent
• atherosclerosis

Pilot studies of in vivo combined intravascular ultrasound (IVUS) and intravascular photoacoustic (IVPA) imaging are reported. A recently introduced prototype of an integrated IVUS/IVPA imaging catheter consisting of a single-element ultrasound transducer and a light delivery system based on a single optical fiber was adapted and used for in vivo imaging of a coronary stent deployed in a rabbit%26apos;s thoracic aorta in the presence of luminal blood. The results suggest that in vivo IVUS/IVPA imaging is feasible using the integrated IVUS/IVPA imaging catheter. The challenges of in vivo combined IVUS/IVPA imaging are discussed, and further improvements on the design of the catheter and the clinical imaging system are proposed.

• 出版日期2012-9