A concise and efficient synthetic strategy to silyl-protected terminal alkynyl sulfides from alkyl or benzyl halides

作者：Safa Kazem D^*; Alyari Maryam

来源：Journal of Organometallic Chemistry, 2015, 781: 1-5.

DOI：10.1016/j.jorganchem.2015.01.012

• Alkynyl sulfides
• Carbon disulfide
• Tris(trimethylsilyl)methyllithium

A novel synthetic strategy to silyl-protected terminal alkynyl sulfides via reaction of lithium 2,2,2-tris(trimethylsilyl) ethanedithioate, produced by the reaction of tris(trimethylsilyl) methyllithium with carbon disulfide, and alkyl or benzyl halides has been developed. The scope of the reaction is broad, with a variety of benzylic and aliphatic halides and products were formed in good to excellent yields.

• 出版日期2015-4-1