Another Shp on the Horizon for Bile Acids

作者：Perino Alessia; Schoonjans Kristina^*

来源：Cell Metabolism, 2014, 20(2): 203-205.

DOI：10.1016/j.cmet.2014.07.019

Bile acid metabolism is tightly controlled due to the toxic effects of bile acid overload. In this issue, research from the Feng lab reports Shp2 as a novel integrator of hepatic bile acid and FGF15/FGF19 signaling, adding another layer of complexity to the control of bile acid biosynthesis.

• 出版日期2014-8-5