Antioxidant and Tyrosinase Inhibitory Constituents from a Desugared Sugar Cane Extract, a Byproduct of Sugar Production

作者：Chung, Yu Ming; Wang, Hui Chun; El Shazly, Mohamed; Leu, Yann Lii; Cheng, Ming Ching; Lee, Chia Lin; Chang, Fang Rong^*; Wu, Yang Chang

来源：Journal of Agricultural and Food Chemistry, 2011, 59(17): 9219-9225.

DOI：10.1021/jf202119m

• desugared sugar cane extract
• Saccharum officinarum
• sugar cane byproduct recycling
• neolignans
• saccharnan A
• saccharnan B
• antioxidant
• free radical scavengers
• tyrosinase inhibitors

Recycling agricultural resources has become an important issue worldwide promoting the economical value of agricultural production processes. Desugared sugar cane extract (DSE) from Saccharum officinarum is a byproduct obtained during sugar production. Two new neolignan glucosides, saccharnan A (1) and saccharnan B (2), together with 10 known phenolics (3-12) were isolated from DSE, and their structures were elucidated on the basis of NMR spectral analysis. Compounds 3, 4, 8, and 9 showed good activity against DPPH radical (IC(50) <= 51.20 mu M) and compounds 3-8 and 12 exhibited strong ABTS( ) free radical scavenging activity (IC(50) <= 51.57 mu M) compared to those of the positive controls, ascorbic acid and Trolox. Moreover, compounds 7 and 12 acted as potent tyrosinase inhibitors (IC(50) <= 42.59 mu M) compared to the positive control arbutin. Our results highlighted the economical value of recycling DSE for the future development of natural antioxidants and/or tyrosinase inhibitors.

• 出版日期2011-9-14
• 单位长春大学; 中国医科大学; 中山大学